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Viagra – The Sensuous Pill!
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Posted On :
Aug-02-2009
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Article Word Count :
522
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This article traces back to history and unravels the details regarding the evolution of Viagra. The working of the pill along with the side effects and social effects are explained clearly.
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Erectile dysfunction was plaguing the life of many men. Prior to 1983, it was thought that erectile dysfunction, the inability to achieve erection, was primarily mental. This theory was refuted by Dr.Giles Brindley. He proved that injecting a drug called phentolamine in the penis provided erection. Viagra made the process simple by creating the same effect using a pill instead of an injection.
The main difference between Viagra over an injection of phentolamine is that Viagra only causes an erection when the man is sexually aroused. The former on the flip side causes an immediate and uncontrolled erection.
If you are suffering from impotence, then you are required to take Generic Cialis .The Cialis helps by relaxing muscles and raising blood flow to particular areas of the body. It can be utilized to treat erectile dysfunction in men. Once after consuming the Cialis, you can achieve and maintain an erection in the time of intercourse.
If you want to create a drug that increases blood flow to the penis, there are at least three ways to do it:
1.Increase the amount of nitric oxide produced in the penis
2.Increase the amount of cGMP produced in the penis in response to the nitric oxide
3.Eliminate the PDE in the penis so that the cGMP builds up instead of getting decomposed by the PDE.
Viagra uses the last method mentioned above. It is found out that the human body boasts of at least 11 different kinds of PDE that it produces. PDE5, one of the kinds, is present primarily in the penis. All that the chemists needed was to find a chemical that would selectively block PDE5 and nothing else. With the PDE5, an enzyme, blocked, cGMP could build up in the penis and increase the blood flow there without affecting other parts of the body.
Pfizer, the manufacturer of Viagra needed a chemical that would gum up PDE5 and keep it from doing its job. He discovered the sildenafil citrate. It gets fit into the PDE5 enzyme and disables it.
Viagra also results in several side effects. The first constraint occurs because Viagra happens to have a spillover effect. It has an effect on PDE6. PDE6 is employed in the cone cells in the retina, so Viagra can cause harmful results on color vision.¬ Several consumers of Viagra have confirmed this effect. Usually pilots are instructed not to consume Viagra within 12 hours of flight.
Next comes for people who are taking drugs like nitroglycerin for angina. It performs by raising nitric oxide, and it aids with angina by unraveling up the arteries that supply the heart with oxygen. You are prone to many complications if you consume nitroglycerin and Viagra together, the increased nitric oxide plus the blocking of PDE5. Presently innumerable numbers of spam e-mail messages are revolving round the internet regarding the sales of Viagra. Most of them are found to be fake. So be alert while purchasing these pills and it is always advisable to take them in a controlled manner!
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Article Source :
http://www.articleseen.com/Article_Viagra – The Sensuous Pill!_2005.aspx
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Author Resource :
The article about generic Viagra is written by author Jack Mark who contributes articles on generic cialis and online Viagra.
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Keywords :
Generic viagra, generic cialis, viagra online,
Category :
Health and Fitness
:
Medicine
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