Can Serum Creatinine Level Reflect Renal Function Accurately?

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Can Serum Creatinine Level Reflect Renal Function Accurately?

Posted On : Dec-15-2011 | seen (601) times | Article Word Count : 505 |

Polycystic Kidney Disease (PKD) is a chronic genetic disease. As the cysts enlarge with age, they will oppress the neighboring kidney tissues thus causing Renal Failure. As kidney has strong sufficient compensatory capacity, the patients do not have symptoms in the early time. Many patients think that if their serum creatinine keeps in the normal range, their renal function must be also normal. In fact, this idea is wrong. Although serum creatinine can reflect the kidney capacity in excreting metabolic wastes and toxins, but it is not sensitive. Only when more than half of patients’ renal function is lost, will the serum level exceed the normal level. The patients with Renal Failure can know their renal function better by the following formula.
Creatinine clearance rate= (140-Age)* body weight (kilogram)*88.4/72*serum creatinine level (umol/L)
If you are women patients, after you get the above result, you should use it to multiply 0.85 then you can get your creatinine clearance rate.
The normal creatinine clearance rate should keep within 80~120 ml/minute. The lower your creatinine clearance rate is, the worse your renal function is.
If your creatinine clearance rate is between 10~15ml/minute, usually your disease has developed into End Stage Renal Failure. It is not proper for patients with Renal Failure to judge their renal function just from their creatinine level. For example, if the two patients have the same creatinine level: 95umol/L, but other factors are different.
Women patient: 75 years old; 50kilogams
Man patient: 25 years old; 75kilogrmas
From the above formula, we can see that the former patients’ creatinine clearance rate is 36umol/L and the latter is 111umol/L. Although the former patient’ renal function has been damaged seriously, but the creatinine level does not reflect it accurately.
Therefore, the patients with Renal Failure should not judge their renal function from their creatinine level simply. They should take other indexes in consideration comprehensively so as to receive effective treatment in the fist time.

From the above introduction, we might have certain knowledge that the high level of serum creatinine is mainly caused by the dysfunction of kidneys caused by the cysts. So, if the kidneys are repaired, serum creatinine level can go down gradually. Thus, a therapy to prevent the growth of kidney cysts and the repair of the kidney units is needed. Traditional Chinese Medicine can be helpful.
There are some natural herbs in Traditional Chinese Medicine which have the function of dilating blood vessel and inactivating the cyst fluid secretion. These functions are exactly needed in the treatment of PKD.

Through a series of processes, the cysts can be shrunk and the kidney function can be repaired. The serum creatinine level will go down gradually. You do not have to suffer from dialysis, which is time-consuming on high expense.
If you meet the following problems and are bothering by the high level of serum creatinine level, you can get advice from our medical staff by clicking our online service. Hope you and a loved one of yours can recover soon.

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<h1> Can Serum Creatinine Level Reflect Renal Function Accurately?</h1> Author: <a href='http://www.articleseen.com/profile_bingllei.aspx'>bingllei</a> Polycystic Kidney Disease (PKD) is a chronic genetic disease. As the cysts enlarge with age, they will oppress the neighboring kidney tissues thus causing Renal Failure. As kidney has strong sufficient compensatory capacity, the patients do not have symptoms in the early time. Many patients think that if their serum creatinine keeps in the normal range, their renal function must be also normal. In fact, this idea is wrong. Although serum creatinine can reflect the kidney capacity in excreting metabolic wastes and toxins, but it is not sensitive. Only when more than half of patients’ renal function is lost, will the serum level exceed the normal level. The patients with Renal Failure can know their renal function better by the following formula.
Creatinine clearance rate= (140-Age)* body weight (kilogram)*88.4/72*serum creatinine level (umol/L)
If you are women patients, after you get the above result, you should use it to multiply 0.85 then you can get your creatinine clearance rate.
The normal creatinine clearance rate should keep within 80~120 ml/minute. The lower your creatinine clearance rate is, the worse your renal function is.
If your creatinine clearance rate is between 10~15ml/minute, usually your disease has developed into End Stage Renal Failure. It is not proper for patients with Renal Failure to judge their renal function just from their creatinine level. For example, if the two patients have the same creatinine level: 95umol/L, but other factors are different.
Women patient: 75 years old; 50kilogams
Man patient: 25 years old; 75kilogrmas
From the above formula, we can see that the former patients’ creatinine clearance rate is 36umol/L and the latter is 111umol/L. Although the former patient’ renal function has been damaged seriously, but the creatinine level does not reflect it accurately.
Therefore, the patients with Renal Failure should not judge their renal function from their creatinine level simply. They should take other indexes in consideration comprehensively so as to receive effective treatment in the fist time.

From the above introduction, we might have certain knowledge that the high level of serum creatinine is mainly caused by the dysfunction of kidneys caused by the cysts. So, if the kidneys are repaired, serum creatinine level can go down gradually. Thus, a therapy to prevent the growth of kidney cysts and the repair of the kidney units is needed. Traditional Chinese Medicine can be helpful.
There are some natural herbs in Traditional Chinese Medicine which have the function of dilating blood vessel and inactivating the cyst fluid secretion. These functions are exactly needed in the treatment of PKD.

Through a series of processes, the cysts can be shrunk and the kidney function can be repaired. The serum creatinine level will go down gradually. You do not have to suffer from dialysis, which is time-consuming on high expense.
If you meet the following problems and are bothering by the high level of serum creatinine level, you can get advice from our medical staff by clicking our online service. Hope you and a loved one of yours can recover soon.
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