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Avoiding lidocain of toxicity

Posted On : Nov-30-2011 | seen (2782) times | Article Word Count : 406 |

Lidocaine is a local anesthetic, which is often used during the administration of anesthesia during medical procedures.
Lidocaine is a local anesthetic, which is often used during the administration of anesthesia during medical procedures. Overdose of this drug leads to toxicity in humans, which may also prove to be fatal. Go through this article to know more about Lidocaine toxicity in humans.

Avoidance of toxicity

Patient education is extremely important so that they are very well aware of toxicity symptoms associated with lidocaine. Notes to immediately contact the physician must be administered to patients, are visible in the event of toxicity symptoms so that prompt treatment can be provided.

The administration of high doses of lidocaine should be performed in a slow manner. For example, each dose of more than 5 ml may be injected in increments of 3 ml, allowing the body to come gradually under the numbing effect of the drug.

Anesthesiologists must be aware of the recommended doses of lidocaine. Lack of knowledge and carelessness can endanger the life of a patient by administering toxic doses of anesthetic.

Maintaining communication with the patient when lidocaine is administered to help in the identification of severe symptoms of poisoning such as, change in mental status, etc. This immediately to prevent further administration of the anesthetic helps.

Lidocaine toxicity depends not only on the dose of anesthetic used, but also the speed with which it is administered, vascularity of the injection site, acidosis and low protein content in the body. Interactions with other drugs can also lead to toxicity. Are propranolol, cimetidine, phenytoin, ciprofloxacin clonidine and some of the drugs that affect lidocaine in the body. Patients with liver dysfunction are more prone to develop toxic effects of lidocaine, because its metabolism in the liver. Impaired liver function to metabolize the anesthetic is not so, the gradual increase of the level in the body.

Report published by the American Association of Poison Control Centers' National Poison Data System, in the year 2007 states that, found 670 children under 6 years that were affected by exposure to lidocaine. In the same report, it was indicated that a total of lidocaine shots229 cases developed minor effects, 83 developed moderate effects and 16 of them were suffering from major toxic effects. There were no deaths in the study reported. This brings us to the conclusion that when lidocaine toxicity is detected at an early stage, the risk of developing serious toxicity results to a large extent can be reduced.

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Keywords : health, medicine,

Category : Health and Fitness : Health and Fitness

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